In the first published results from a clinical trial using human embryonic stem cells, two legally blind patients who received an injection of hESC-derived cells in one eye have experienced no harmful side effects and appear to have slightly better vision. Although the result is preliminary, it is an important milestone for the struggling hESC field.
Hitching a ride into the retina on nanoparticles called dendrimers offers a new way to treat age-related macular degeneration and retinitis pigmentosa. A collaborative research study among investigators at Wayne State University, the Mayo Clinic and Johns Hopkins Medicine shows that steroids attached to the dendrimers targeted the damage-causing cells associated with neuroinflammation, leaving the rest of the eye unaffected and preserving vision.
A telescopic implant that fits directly into the eye to treat certain kinds of blindness has finally received FDA approval for use in the US after more than five years of waiting. The Implantable Miniature Telescope (IMT) is used to treat age-related macular degeneration (AMD), a condition that affects millions around the world. For many, the center part of their vision becomes blurred or completely dark. The IMT is surgically implanted into the cornea and acts to expand an incoming image onto the peripheral parts of the retina that are undamaged by AMD.
